News & Events / Publications
28 November 2017
Daveson, J., et al. Epitope-Specific Immunotherapy Targeting CD4-Positive T Cells in Celiac Disease: Safety, Pharmacokinetics, and Effects on Intestinal Histology and Plasma Cytokines with Escalating Dose Regimens of Nexvax2 in a Randomized, Double-Blind, Placebo-Controlled Phase 1 Study. EBioMedicine. 2017; [Epub].
11 May 2017
Goel, G., et al. Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies. Lancet Gastroenterol Hepatol. 2017; [Epub ahead of print].
8 March 2017
Cook, L., et al. Circulating gluten-specific FOXP3+ CD39+ regulatory T cells have impaired suppressive function in patients with celiac disease. J Allergy Clin Immunol. 2017; [Epub ahead of print].
28 July 2015
Hardy, M.Y., et al. Consistency in Polyclonal T-cell Responses to Gluten Between Children and Adults With Celiac Disease. Gastroenterology. 2015; 149(6): 1541-52.
1 November 2014
Hardy, M.Y., et al. Ingestion of oats and barley in patients with celiac disease mobilizes cross-reactive T cells activated by avenin peptides and immuno-dominant hordein peptides. J Autoimmun. 2015; 56: 56-65.
3 January 2014
Ontiveros, N., Tye-Din, J.A., Hardy, M.Y., and Anderson, R.P. Ex-vivo whole blood secretion of interferon (IFN)-γ and IFN-γ-inducible protein-10 measured by enzyme-linked immunosorbent assay are as sensitive as IFN-γ enzyme-linked immunospot for the detection of gluten-reactive T cells in human leucocyte antigen (HLA)-DQ2·5+-associated coeliac disease. Clin Exp Immunol. 2014; 175(2): 305-15.
28 April 2014
Petersen, J., et al. T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease. Nat Struct Mol Biol. 2014; 21(5): 480-8.
28 August 2013
Anderson, R.P., et al. A novel serogenetic approach determines the community prevalence of celiac disease and informs improved diagnostic pathway. BMC Medicine. 2013; 11:188.
15 March 2013
Sollid, L.M., and Jabri, B. Triggers and drivers of autoimmunity: lessons from coeliac disease. Nat Rev Immunol. 2013; 13: 294-302.
13 March 2013
Anderson, R.P., and Jabri, B. Vaccine against autoimmune disease: antigen-specific immunotherapy. Cur Opin Immunol. 2013; 25(3): 410-7.
11 October 2012
Broughton, S.E., et al. Biased T Cell Receptor Usage Directed against Human Leukocyte Antigen DQ8-Restricted Gliadin Peptides Is Associated with Celiac Disease. Immunity. 2012; 37(4): 611-21.
21 July 2010
Tye-Din, J.A., et al. Comprehensive, Quantitative Mapping of T Cell Epitopes in Gluten in Celiac Disease. Sci Transl Med. 2010; 2(41): 41ra51.
11 September 2005
Anderson, R.P., et al. T-cells in peripheral blood after gluten challenge in coeliac disease. Gut. 2005; 54:1217-1223.
1 March 2000
Anderson, R.P., et al. In vivo antigen challenge in celiac disease identifies a single
transglutaminase-modified peptide as the dominant AgliadinT-cell epitope. Nature Medicine. 2000; 6(3):337-42.